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전이성 유방암이란

유방암은 초기 진단 및 치료 후 몇 달 또는 몇 년 후(때로는 20년 이후)에 신체의 다른 부분으로 전이될 수 있습니다.
유방암이 전이되면 암세포가 림프관이나 혈류로 들어가 림프절이나 다른 기관으로 퍼집니다.

전이는 유방암 세포가 순환계를 통해 이동하고 미세전이암이라고 불리는 새로운 암 침윤을 일으킬 때 발생합니다.
이 작은 종양은 처음에는 탐지하기에는 너무 작지만, 시간이 지남에 따라 세포는 새로운 위치에서 분열을 계속할 수 있습니다.
분열 세포가 형성하는 종양은 특정 크기 이상으로 커질 때만 스캔하여 발견할 수 있으므로 명확한 스캔으로 암세포를 발견하지 못했더라도 암이 없다는 것을 의미하지는 않습니다.

유방암은 초기 진단 및 치료 후 몇 달 또는 몇 년 후(때로는 20년 이후)에 신체의 다른 부분으로 전이될 수 있습니다.
유방암이 전이되면 암세포가 림프관이나 혈류로 들어가 림프절이나 다른 기관으로 퍼집니다.

전이는 유방암 세포가 순환계를 통해 이동하고 미세전이암이라고 불리는 새로운 암 침윤을 일으킬 때 발생합니다.
이 작은 종양은 처음에는 탐지하기에는 너무 작지만, 시간이 지남에 따라 세포는 새로운 위치에서 분열을 계속할 수 있습니다.
분열 세포가 형성하는 종양은 특정 크기 이상으로 커질 때만 스캔하여 발견할 수 있으므로 명확한 스캔으로 암세포를 발견하지 못했더라도 암이 없다는 것을 의미하지는 않습니다.

새로 발견된 1기 암세포는 유방에서 멀리 이동하여 쉽게 혈류에 들어갈 수 있지만, 일부만이 다른 기관에서 생존하고 성장할 수 있습니다.
일반적으로 몸은 세균과 같이 인식하지 못하는 것을 거부하거나 공격하지만, 전이의 경우에는 암세포가 충분히 익숙해 져서 신체의 여러 영역에서 성장할 수 있습니다.
유방암 전이의 가장 일반적인 위치는 간, 뼈, 폐 및 뇌입니다.

많은 의사가 전이 과정을 연구했지만, 현재까지 아무도 암세포가 성장하기 전에 얼마나 오래 비활성 상태인지 예측할 수 없습니다.
하지만, 수년에 걸쳐 유방암의 진단과 치료에 상당한 개선과 진보가 있었습니다.
실제로, 유방암은 이제 관리 가능한 질병으로 간주됩니다.

그러나 여전히 전 세계적으로 50만 명이 넘는 유방암 사망자가 있으며, 그중의 90%이상의 여성이 전이성 유방암으로 사망합니다.
결과적으로, 전이에 관한 연구는 전이성 유방암으로 인한 사망을 극복하는 데 매우 중요합니다.

많은 의사가 전이 과정을 연구했지만, 현재까지 아무도 암세포가 성장하기 전에 얼마나 오래 비활성 상태인지 예측할 수 없습니다.
하지만, 수년에 걸쳐 유방암의 진단과 치료에 상당한 개선과 진보가 있었습니다.
실제로, 유방암은 이제 관리 가능한 질병으로 간주됩니다.

그러나 여전히 전 세계적으로 50만 명이 넘는 유방암 사망자가 있으며, 그중의 90%이상의 여성이 전이성 유방암으로 사망합니다.
결과적으로, 전이에 관한 연구는 전이성 유방암으로 인한 사망을 극복하는 데 매우 중요합니다.

연구 결과에 따르면 전이성 유방암의 경우 “조기 발견”이라는 개념이 적용되지 않습니다.
증상이 나타나기 전에 종양 표지 검사와 스캔을 통해 암의 진행을 확인하고 몇 달 전에 치료하더라도 아무런 이점이 없습니다.
전이성 유방암은 대개 치료에 매우 민감하며 많은 치료법이 있지만, 대다수의 경우 완벽한 치료가 불가능하므로 만성 질환으로 보고, 수년 동안 잘 통제되어야 합니다.

암세포가 신체의 다른 영역으로 퍼졌지만, 의사는 여전히 유방암으로써 치료할 것입니다.
뼈 전이로 진단받는 것은 뼈 암으로 진단받는 것이 아닙니다. 현미경 하에서 암세포는 여전히 유방암 세포와 동일하게 보입니다.
비록 암세포가 먼 곳에서 자라고 있지만, 이 세포들은 유방에서 암을 유발한 세포들과 동일한 돌연변이와 유사한 유전자 구성을 가지고 있습니다.

전이는 동시에 여러 위치에서 또는 단일 위치에서 발생할 수 있습니다.
전이성 유방암은 “전신적인” 질병으로 간주됩니다. 적어도 전이가 발견된 부위 이상으로 암이 퍼졌다고 추정됩니다.
이것은 수술이나 방사선 같은 국부적인 치료가 시도될지, 아니면 전신에 영향을 미치는 약물이 사용되는지 여부에 중요한 영향을 미칩니다.

전이성 유방암의 치료는, 가능한 한 오랫동안 암을 줄이거나 약화시키고 증상과 부작용을 관리하고 암이 더 퍼지지 않도록 방지하면서 암을 통제하는 것과, 삶의 질을 최대한 높이는 두 가지 목표를 가지고 있습니다.

치료의 변화는 암이 자라거나 신체의 새로운 곳으로 퍼지면서 이루어집니다.
환자와 의사는 유방암의 진행, 종양의 성장 또는 암의 확산, 퇴행, 종양 크기의 감소 또는 암의 도달에 대해 정기적으로 이야기해야 합니다.
한 가지 치료가 중단되면 환자와 의사는 새로운 옵션을 찾게 됩니다.

또한 평상시의 일상 활동을 유지하고 즐기는 것에 참여할 수 있다는 것은 전반적인 생활 안정에 필수적입니다.
증상 및 부작용이 매일 환자에게 미치는 영향에 대해 의료진과 공개적으로 이야기하는 것이 도움이 될 수 있습니다.

a

DR CATHERINE CASTILLO

Neurologist

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